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We study the pathogenesis of human chlamydial infections

The bacterium Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infection (STI) throughout the world. Chlamydia infection rates are high and continue to rise. Prior to COVID, Chlamydia infections were the most commonly reported infection in the US. Chlamydia disproportionately affects young women and people from disadvantaged backgrounds for the development of severe reproductive outcomes. While effective treatments exist, there is no preventative vaccine, and much remains to be learned about how this pathogen causes disease in humans.

The goals of our research are to define the critical bacterial and host factors responsible for Chlamydia infections and chronic clinical outcomes.

Lab overview

Mechanisms of Chlamydia pathogenesis

A major research focus in our lab is to solve how the major human pathogen Chlamydia manipulates host cell function in order to cause infectious disease. We apply a diverse array of genetic, cellular, and molecular techniques to reveal the underlying mechanisms of pathogenesis for these highly successful bacteria.

Active areas of research:

Chlamydia functional genomics

Chlamydia–host interactions

Clinical history of Chlamydia infections

Read more about our research

News

Posted on

A fresh coat of paint

A refreshing of our lab website was long overdue, and so today marks the beginning of Hybiskelab v3.0. For historical record keeping, v1.0 was a home-brew, self-hosted version and v2.0 was hosted for several serviceable years at Squarespace. From a design standpoint, Squarespace is simply wonderful and powerful. Alas, with means expired to subsidize their …

Continue reading “A fresh coat of paint”

Contact

The Hybiske Lab is located at the UW Medicine – South Lake Union research cluster, situated near picturesque Lake Union, the Space Needle, the Center for Infectious Disease Research, the Allen Institute, Fred Hutch, and downtown Seattle.

Address

750 Republican Street
Seattle, WA, 98109
United States

Contact

khybiske[at]uw.edu
206-616-1549

INTERESTED IN JOINING?

The Hybiske lab is always interested in hearing from innovative individuals: prospective graduate students, postdocs, fellows, and undergraduate students. We are part of an unparalleled nexus of interdepartmental research expertise in microbial pathogenesis, infectious diseases, and global health at the University of Washington.

PROSPECTIVE GRADUATE STUDENTS

You must apply (and be accepted by) the Pathobiology PhD Program.

UNDERGRADUATE STUDENTS

UW students majoring in Microbiology or similar areas are encouraged to appy. Contact Kevin by email to inquire about possible openings. Please provide a copy of your current academic transcript, a resume, and a detailed statement of why you are a good fit for our possible needs.

🚨 Nov 2022 update 🚨

We are in need of undergraduate research volunteer(s) to help with a short-term project. This project requires 1-2 full days per week at SLU. Inquire if interested.