Hybiske Lab

Publications

Peer-reviewed research from the Hybiske Lab spanning functional genomics, host–pathogen biology, and clinical Chlamydia infections.

2024
Comparison of IgG serum antibodies, electronic health records and self-report in estimating past infection with Chlamydia trachomatis in a cohort of men who have sex with men
Waters MB, Barbee LA, Hybiske K, Newman K, Ikeda R, LeClair A, Golden MR, Soge OO, Manhart LE, Khosropour CM
Sexual Health · 2024 · PMID 39621456
Development of a lambda Red based system for gene deletion in Chlamydia
Wang Y, Suchland R, Hua A, Carrell S, Rockey D, Hybiske K
PLoS One · 2024 · PMID 39541273
Chlamydia trachomatis seroassays used in epidemiologic research: a narrative review and practical considerations
Waters MB, Hybiske K, Ikeda R, Kaltenboeck B, Manhart LE, Kreisel KM, Khosropour CM
Journal of Infectious Diseases · 2024 · PMID 39052727
CT135 mediates the resistance of Chlamydia trachomatis to primate interferon gamma stimulated immune defenses
Fernandez MC, Sweeney YC, Suchland RJ, Carrell SJ, Soge OO, Phan IQ, Rockey DD, Patton DL, Hybiske K
iScience · 2024 · PMID 38947519
Antibodies from chlamydia-infected individuals facilitate phagocytosis via Fc receptors
Hybiske K, Paktinat S, Newman K, Patton D, Khosropour C, Roxby AC, Mugo NR, Oluoch L, Ngure K, Suchland R, Hladik F, Vojtech L
Infection and Immunity · 2024 · PMID 38451079
2022
Genomic analysis of MSM rectal Chlamydia trachomatis isolates identifies predicted tissue-tropic lineages generated by intraspecies lateral gene transfer-mediated evolution
Suchland RJ, Carrell SJ, Ramsey SA, Hybiske K, Debrine AM, Sanchez J, Celum C, Rockey DD
Cover Artwork
Infection and Immunity · 2022 · PMID 36214558
Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx
Maddy J, Staker BL, Subramanian S, Abendroth J, Edwards TE, Myler PJ, Hybiske K, Asojo OA
Acta Crystallographica Section F · 2022 · PMID 35234139
2021
A broad-spectrum cloning vector that exists as both an integrated element and a free plasmid in Chlamydia trachomatis
Garvin L, Vande Voorde R, Dickinson M, Carrell S, Hybiske K, Rockey D
PLoS One · 2021 · PMID 34914750
Rectal Chlamydia trachomatis Infection: A Narrative Review of the State of the Science and Research Priorities
Khosropour CM, Dombrowski JC, Vojtech L, Patton DL, Campbell LA, Barbee LA, Franzi MC, Hybiske K
Sexually Transmitted Diseases · 2021 · PMID 34475361
Inter-species lateral gene transfer focused on the Chlamydia plasticity zone identifies loci associated with immediate cytotoxicity and inclusion stability
Dimond ZE, Suchland RJ, Baid S, LaBrie SD, Soules KR, Stanley J, Carrell S, Kwong F, Wang Y, Rockey DD, Hybiske K, Hefty PS
Cover Artwork
Molecular Microbiology · 2021 · PMID 34738268
Priorities for sexually transmitted infection vaccine research and development: Results from a survey of global leaders and representatives
Plotnikoff KM, Donken R, Smith L, Cameron C, LaMontagne DS, Bettinger JA, Sadarangani M, Grennan T, Racey CS, Hybiske K, Naus M, Monteiro A, Ogilvie GS
Vaccine X · 2021 · PMID 34401741
2020
Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis
Barrett KF, Dranow DM, Phan IQ, Michaels SA, Shaheen S, Navaluna ED, Craig JK, Tillery LM, Choi R, Edwards TE, Conrady DG, Abendroth J, Horanyi PS, Lorimer DD, Van Voorhis WC, Zhang Z, Barrett LK, Subramanian S, Staker B, Fan E, Myler PJ, Soge OO, Hybiske K, Ojo KK
Protein Science · 2020 · PMID 31930578
2019
Development of Transposon Mutagenesis for Chlamydia muridarum
Wang Y, LaBrie SD, Carrell SJ, Suchland RJ, Dimond ZE, Kwong F, Rockey DD, Hefty PS, Hybiske K
Journal of Bacteriology · 2019 · PMID 31501283
Chromosomal Recombination Targets in Chlamydia Interspecies Lateral Gene Transfer
Suchland RJ, Carrell SJ, Wang Y, Hybiske K, Kim DB, Dimond ZE, Hefty PS, Rockey DD
Journal of Bacteriology · 2019 · PMID 31501285
Recurrent/Intermittent Vaginal and Rectal Chlamydial Infection Following Treatment: A Prospective Cohort Study Among Female Sexually Transmitted Disease Clinic Patients
Khosropour CM, Soge OO, Suchland R, Leipertz G, Unutzer A, Pascual R, Hybiske K, Barbee LA, Manhart LE, Dombrowski JC, Golden MR
Journal of Infectious Diseases · 2019 · PMID 30873541
Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites
Dickinson MS, Anderson LN, Webb-Robertson BM, Hansen JR, Smith RD, Wright AT, Hybiske K
PLOS Pathogens · 2019 · PMID 31130662
The Chlamydia trachomatis Extrusion Exit Mechanism Is Regulated by Host Abscission Proteins
Zuck M, Hybiske K
Microorganisms · 2019 · PMID 30943267
ChlamBase: a curated model organism database for the Chlamydia research community
Putman T, Hybiske K, Jow D, Afrasiabi C, Lelong S, Cano MA, Stupp GS, Waagmeester A, Good BM, Wu C, Su AI
Database · 2019 · PMID 31211397
2018
Direct visualization of the expression and localization of chlamydial effector proteins within infected host cells
Wang X, Hybiske K, Stephens RS
Pathogens and Disease · 2018 · PMID 29390129
2017
Orchestration of the mammalian host cell glucose transporter proteins-1 and 3 by Chlamydia contributes to intracellular growth and infectivity
Wang X, Hybiske K, Stephens RS
Pathogens and Disease · 2017 · PMID 29040458
Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State
McFarland AP, Luo S, Ahmed-Qadri F, Zuck M, Thayer EF, Goo YA, Hybiske K, Tong L, Woodward JJ
Immunity · 2017 · PMID 28329705
Extrusions are phagocytosed and promote Chlamydia survival within macrophages
Zuck M, Ellis T, Venida A, Hybiske K
Cellular Microbiology · 2017 · PMID 27739160
Chlamydia trachomatis Cellular Exit Alters Interactions with Host Dendritic Cells
Sherrid AM, Hybiske K
Infection and Immunity · 2017 · PMID 28223346
Selected older papers
Conservation of extrusion as an exit mechanism for Chlamydia
Zuck M, Sherrid A, Suchland R, Ellis T, Hybiske K
Pathogens and Disease · 2016 · PMID 27620201
Exit strategies of intracellular pathogens
Hybiske K, Stephens RS
Nature Reviews Microbiology · 2008 · PMID 18197167
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells
Hybiske K, Stephens RS
Infection and Immunity · 2007 · PMID 17592133
Mechanisms of host cell exit by the intracellular bacterium Chlamydia
Hybiske K, Stephens RS
Proceedings of the National Academy of Sciences · 2007 · PMID 17502389